Protein Modification Reagents
Medchemexpress LLC Biotin alkyne | 773888-45-2 | MFCD28385487 | 98.6% | 281.37 | C13H19N3O2S | 5 MG
Biotin alkyne is a biotin-labeled, PEG-based linker containing a terminal alkyne for copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is designed for introducing biotin tags in PROTAC synthesis, bioconjugation, and affinity capture workflows, and is supplied at high purity for research-scale applications.
- Contains a terminal alkyne for CuAAC
- Facilitates biotin labeling for affinity capture and detection
- Peg-based linker provides solubility and flexibility
- High purity suitable for synthesis and analytical use
- Available in small quantities for research-scale workflows
eMolecules 109635-64-5 | Tos-PEG10-Tos | Broadpharm | MFCD25372003 | 722.860 | C32H50O14S2 | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1 | 1g | 229582273
Tos-PEG10-Tos | Broadpharm | 109635-64-5 | MFCD25372003 | 722.860 | C32H50O14S2 | 98.000 | Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1 | 1g | 229582273
![Medchemexpress LLC Acetic acid, 2-[(18-chloro-3,6,9,12-tetraoxaoctadec-1-yl)oxy]- | 1799506-30-1 | 98.0% | 370.87 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000439158-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Acetic acid, 2-[(18-chloro-3,6,9,12-tetraoxaoctadec-1-yl)oxy]- | 1799506-30-1 | 98.0% | 370.87 | 250 MG
Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker designed for the synthesis of chloroalkane-containing PROTACs, also known as HaloPROTACs. PROTACs function by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker.
- Used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs).
- Facilitates selective degradation of target proteins via the ubiquitin-proteasome system.
Medchemexpress LLC Alkyne-PEG2-iodide | 1234387-33-7 | C7H11IO2 | 100 MG
Alkyne-PEG2-iodide | 1234387-33-7 | C7H11IO2 | 100 MG
ABclonal Technology SREK1 Rabbit pAb
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Medchemexpress LLC Azido-PEG6-MS | 352439-38-4 | MFCD34471264 | >95.0% | 385.43 | C13H27N3O8S | 5 MG
Azido-PEG6-MS is an azide-terminated PEG6 linker used as a click-chemistry reagent and in PROTAC linker synthesis. It provides a short, flexible, hydrophilic spacer with a terminal azide that enables copper-catalyzed or strain-promoted azide-alkyne cycloaddition for attaching small molecules or biomolecules in medicinal chemistry and bioconjugation applications.
- Contains an azide functional group for click chemistry reactions.
- Provides a PEG6 spacer for hydrophilicity and conformational flexibility.
- Suitable for PROTAC linker synthesis and bioconjugation workflows.
- Supplied in small-scale quantities appropriate for research use.
- Compatible with common conjugation conditions, including CuAAC.
Medchemexpress LLC Protac EGFR degrader 4 | 2882845-50-1 | 99.7% | 995.29 | C55H70N12O4S | 5 MG
PROTAC designed to selectively target and induce degradation of mutant forms of the epidermal growth factor receptor (EGFR). Demonstrates potent degradation of EGFRdel19 and EGFRL858R/T790M in cellular assays and inhibits growth of EGFR-driven cancer cell lines. Supplied as a high-purity research reagent with recommended solvent and storage conditions.
- Targets mutant EGFR, inducing degradation of activating and resistance variants.
- Demonstrated cellular potency with low-nanomolar DC50 values.
- High reported purity suitable for biochemical and cellular studies.
- Soluble in DMSO at 100 mg/mL; may require ultrasonic treatment.
- Store protected from light and under inert atmosphere; in solvent: -80°C (6 months), -20°C (1 month).