Protein Modification Reagents
Medchemexpress LLC Ald-Ph-amido-PEG4-C2-NHS ester | 1353011-74-1 | 98.1% | 494.49 g/mol | C23H30N2O10 | 100 MG
Ald-Ph-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit polyethylene glycol (PEG) linker functionalized as an N-hydroxysuccinimide (NHS) ester for amine-reactive bioconjugation in antibody-drug conjugate (ADC) development. It is supplied for research use and is typically stored at low temperature.
- Non-cleavable 4-unit PEG linker for stable conjugation.
- NHS ester functional group for amine-reactive coupling.
- Molecular weight 494.49 g/mol.
- Molecular formula C23H30N2O10.
- CAS number 1353011-74-1.
- High purity (≈98.1%) suitable for research applications.
- Available in multiple package sizes from 50 mg to 10 g.
Cayman Chemical CLS-MPEG 2000 100mg
A PEGylated form of cholesterol; has been used in the synthesis of liposomes for targeted drug delivery
Medchemexpress LLC DSPE-PEG-maleimide | 00-00-0 | 99.5% | 10MG
DSPE-PEG-maleimide (MW 5000) is a pegylated phospholipid that combines a DSPE lipid anchor with a PEG spacer terminated in a maleimide group for selective thiol conjugation. Supplied as a solid powder with high purity, it is designed for incorporation into liposomes and lipid nanoparticles and for attaching thiol-containing ligands and peptides to particle surfaces.
- Molecular weight ~5,000 for predictable spacer length.
- Maleimide functional group enables selective thiol conjugation.
- DSPE lipid anchor allows stable insertion into lipid bilayers.
- PEG spacer increases circulation time and stability of formulations.
- High purity (~99.5%) suitable for research and formulation work.
- Powder form with recommended storage at -20°C for long-term stability.
Cayman Chemical ANTIBODY DBCO acId 500mg
A copper-free click chemistry reagent; has been used in the study of glycoprotein charge effects on the migration and invasion of 9-azido sialic acid-labeled cancer cells in vitro; has also been used in the synthesis of DBCO-modified RNase A to deliver RNase A into AAM-labeled cancer cells in vitro and in vivo to induce cytotoxicity and reduce tumor growth, respectively
Medchemexpress LLC Dota-PEG5-azide | 00-00-0 | 98.0% | C28H52N8O12 | 10MG
DOTA-PEG5-azide is a PEG-based linker that combines a DOTA chelator with an azide functional group for click-chemistry conjugation. Supplied as a white to off-white solid, it is intended for use in PROTAC synthesis, bioconjugation, and radiolabeling workflows where a chelator and a click-reactive handle are required.
- Contains DOTA chelator suitable for metal chelation and radiolabeling.
- Azide functional group enables copper-catalyzed and strain-promoted click reactions.
- PEG5 spacer improves solubility and reduces steric hindrance in conjugates.
- High purity (98.0%) for research-grade synthesis.
- Available in small-scale quantities compatible with iterative synthesis workflows.
Biotium Insulin(E2-E3), CF594 conjugate, 0.1mg/mL
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have